Basic science and Pharmacology
New Technology
Atrial Fibrillation: Pharmacology and Clinical trials of Anticaogulants
Pacing & ICD Therapy: New technology (wireless devices and MRI safe devices and leads, applications of remote monitoring, current Registries and clinical trials) Ventricular Fibrillation and Sudden Death

Catheter ablation: clinical trials
Heart failure clinical trials
Outcomes and Clinical Trials in Electrophysiology and Pacing

INTERNATIONAL FACULTY
Martin Bergmann, Hamburg, Germany
Leif-Hendrik Boldt, Berlin, Germany
Johannes Brachmann, Coburg, Germany
A. John Camm, London, United Kingdom
Riccardo Cappato, Milan, Italy
Isabell Deisenhofer, Munich, Germany
Thomas Deneke, Bad Neustadt, Germany
Dobromir Dobrev, Essen, Germany
Uwe Dorwarth, Munich, Germany
Nico Doll, Stuttgart, Germany
Michael Ezekowitz, Wynnewood, PA, US
Andreas Goette, Paderborn, Germany
Gerhard Hindricks, Leipzig, Germany
Ellen Hoffman, Munich, Germany
Werner Jung, Villingen, Germany
Raj Kaushik, Passaic, NJ, US
Helmut Klein, Munich, Germany
Dhanunjay Lakireddy, Kansas City, KS, US
Thorsten Lewalter, Munich, Germany
Sam Levy, Marseille, France
Berndt Lüderitz, Bonn, Germany
Davendra Mehta, New York, NY
Gerald Naccarelli, Hershey, PA, US
Randy Nagarakanti, New Orleans, LA, US
Sanjiv Narayan, San Diego, CA, US
Andrea Natale, MD, Austin, TX, US
Georg Nölker, Bad Oeynhausen, Germany
Arne Pfeufer, Munich, Germany
Stefan Sack, Munich, Germany
Sanjeev Saksena, New Brunswick, NJ, US
Kamal Sethi, New Delhi, India
Balbir Singh, New Delhi, India
April Slee, MS, Warren, NJ, US
Gerhard Steinbeck, Munich, Germany
Klaus Tiemann, Munich, Germany
Ernst Vester, Duesseldorf, Germany
Stephen Wildhirt, Munich, Germany
Stephan Willems, Hamburg, Germany

8:00-10:00
(Co-Chairs): Klaus Tiemann & Balbir Singh
8:00-8:20 Intracardiac Echocardiography: How to perform ICE guided CRT & LAA imaging
from new imaging windows:
Sanjeev Saksena
8:20-8:40
Cardiac MRI and Cardiac CT: How to integrate into the EP Lab
Klaus Tiemann
8:40-9:00
Case Demonstration: Role of 3D TEE to guide interventional procedures
Klaus Tiemann
9:00-9:20
Case Demonstration: CT reconstruction of LAA morphologies
Andrea Natale
9:20-9:40
Case Demonstration: How to perform rotor mapping-the TOPERA technique:
Sanjiv Narayanan
9:40-10:00
Case Demonstration: High-density mapping of AF – the RHYTHMIA experience
tbd
10:00-10:20
Mapping and Ablation of VF: How and For Whom:
Stephan Willems
10:30-11:00
COFFEE BREAK
11:00-12:30
(Co-Chairs): Johannes Brachmann & Sanjeev Saksena
11:00-11:20
New techniques for Robotic Navigation in AF
Andrea Natale
11:20-11:40
Robotic Navigation with the Hansen system: Learning curves and lessons learned
Werner Jung
11:40-12:00
Case Demonstration: VF Ablation using Stereotaxis magnetic robotic navigation system
Georg Nölker
12:00-12:15
Case Demonstration: The “Mediguide” Mapping & Ablation Experience
Gerhard Hindricks
12:15-12:30
Case Demonstration: Catheter Ablation using the Amigo Robotic Navigation system using an open
architecture ablation catheter concept
Leif-Hendrik Boldt
12:30-13:30
LUNCH

Workshop 2: New Directions in Antiarrhythmic Therapy and Stroke Prevention
8:00-10:00
(Co-Chairs): Eckhard Alt & Dobromir Dobrev
8:00-8:30
Dronedarone: guideline position and current clinical use
Andreas Goette
8:30-9:00
New Targets for Antiarrhythmic Drug Therapy: Atrial specific agents and substrate modifiers:
Dobromir Dobrev
9:00-9:30 Fundamentals of cardiac regeneration and repair
Eckhard Alt
9:30-10:00
PANEL DISCUSSION
10:00-10:30
COFFEE BREAK
10:30-12:30
(Co-Chairs): Michael Ezekowitz & Ernst Vester
10:30-11:00
Second Generation NOACs: Pharmacology and Clinical Trials
Michael Ezekowitz
11:00-11:20
Cardioversion of Atrial Fibrillation: Is Dabigatran preferable to Warfarin – The RE-LY Experience:
Rangadham Nagarakanti
11:20-11:45
Factor X inhibitors Rivaroxaban and Apixaban: Clinical trials and application
Ernst Vester
11:45–12:00
Clinical Indication for left atrial appendage occlusion
Thorsten Lewalter
12:00-12:15
Case Demonstration: Amplatzer device implantation
Thorsten Lewalter
12:15-12:30
PANEL DISCUSSION
12:30-13:30
LUNCH

Workshop 3: Advanced Catheter Ablation in AF and VT/VF – New Technologies and Intervention Targets
13:30-18:00
(Co-Chairs): Andrea Natale & Gerhard Hindricks
13:30-14:00
“State of the Art lecture”: Established and Upcoming Technology for PV Disconnection
Andrea Natale
14:00-14:15
Case Demonstration: Cryo Balloon Technology
Uwe Dorwarth
14:15-14:30
Case Demonstration: Endoscopic Laser Balloon Ablation
Thorsten Lewalter
14:30-14:45
PANEL DISCUSSION
14:45-15:15
COFFEE BREAK
15:15-15:45
“State of the Art lecture”: Substrate Identification and Ablation Strategy in persistent AF
Michel Haissaguerre
15:45-16:00
Case Demonstration: Ablation of Human AF Rotors
Sanjiv Narayan
16:00-16:15
Case Demonstration: Ablation of CFAE´s
Isabell Deisenhofer
16:15-16:30
Case Demonstration: Hybrid therapy for AF treatment
Sanjeev Saksena
16:30-16:45
PANEL DISCUSSION
(Co-Chairs):
Raj Kaushik & Nico Doll
16:45-17:15
“State of the Art lecture”: Ablation in in persistent AF – the surgeons perspective
Nico Doll
17:15-17:30
Case Demonstration: Endoscopic Surgical AF Ablation as part of a hybrid strategy
Stephen Wildhirt
17:30-17:45
Case Demonstration: Stand alone surgical AF ablation
Nico Doll
17:45-18:00
PANEL DISCUSSION and WRAP-UP

Workshop 4: New Devices for Rhythm Monitoring, Bradycardia, Heart Failure and Hypertension
13:30-14:45
(Co-Chairs): Gerhard Steinbeck & Sanjeev Saksena
13:30-14:00
Leadless Microimplants for Pacing and Continous Rhythm
Monitoring and Case Demonstration
tbd
14:00-14:30
Experience with MRI Safe Devices:
Werner Jung
14:10-14:45
Case Demonstration: Renal Denervation

• • • St. Jude System tbd
    • Boston System tbd
    • Laser Lead Extraction

  Raj Kaushik

14:45-15:15
COFFEE BREAK
15:15-17:00
(Co-Chairs): Kamal Sethi & Andreas Goette
15:15–15:30
Clinical Experience with Subcutaneous defibrillator:
Riccardo Cappato
15:30-15:50
Wireless Telemetry and Remote Monitoring of ICDs/CRT´s:
Practical implementation and environmental interactions:
Stefan Sack
15:50-16:10
Cardiac Contractility Modulation/CCM – Pathophysiology, clinical trials and Case demonstration
tbd
16:10-16:30
Bridge therapy in Defibrillation – Increasing role of the LIFEVEST concept.
Helmut Klein
16:30-16:45
Case Demonstration: Subcutaneous ICD implantation
Riccardo Cappato
16:45-17:00
Case Demonstration: Intraoperative Optimization of CRT with ICE
Sanjeev Saksena
17:45-18:00
PANEL DISCUSSION and WRAP-UP

8:00
Welcome: T Lewalter/S Saksena
Opening Plenary Session
Interventional EP: Past, Present and Future
(Co-Chairs): John Camm and Gerald Naccarelli
8:10-8:25
Introduction: Symposium on Interventional Electrophysiology:
T Lewalter & B Lüderitz
8:25–8:45
Welcome Adress
tbd
8:45-9:00
Keynote Lecture: Thromboembolic risk in Interventional
Electrophysiology Practice: Recent Advances in Diagnosis and Management
Michael Ezekowitz
9:00-10:40
Session I: Advances in Basic Science and Regenerative Medicine
(Co-Chairs): M Bergmann / D Dobrev
9:00-9:30
Genetics in AF – Current Understanding
A Pfeufer
9:30-10:00
The Atrial Substrate and Novel molecular targets for AF therapy
D Dobrev
10:00-10:30
Stem Cell Therapy for Heart Disease: Current Clinical Status
M Bergmann
10:30-11:00
COFFEE BREAK
11:00-13:00
Session II: New Technologies in Catheter Ablation
(Co-Chairs): S Saksena / S Willems
11:00 – 11:20
Mediguide – Impact on Catheter Ablation Techniques and Workflow
D Lakireddy
11:20-11:40
Stereotactic and Robotic Systems for Catheter Manipulation
G Nölker
11:40-12:00
Endoscopic Ablation Systems
T Lewalter
12:00-12:30
Renal Denervation – New Tools and new applications
tbd
12:30-13:00
Contact force measurement – the final missing link in catheter ablation?
tbd
13:00-14:00
LUNCH
14:00-15:50
Session III: Atrial Fibrillation: Pharmacology and Clinical trials of Anticaogulants
(Co-Chairs): M Ezekowitz & J Brachmann
14:00-14:20
Clinical Trials with Atrial Specific Agents
D Dobrev
14:20-14:40
RAAS Inhibitors and Fish Oils: Do They Have a Role in Preventing AF?
G Naccarelli
14:40-15:00
Newer antithrombotics and their antidotes: current status
S Lévy 15:00-15:30
Keynote Lecture: Guidelines for antiarrhythmic and anticoagulant therapy:
Trial evidence versus Post marketing Surveillance
AJ Camm
15:30-15:50
PANEL DISCUSSION
15:50-16:15
COFFEE BREAK
16:15-18:00
Session IV: Pacing and Defibrillation
(Co-Chairs): S Saksena & B Lüderitz
16:15-17:10
Left ventricular or biventricular pacing? Single or multielectrode leads? An implanter’s viewpoint
K Sethi
17:10-17:30
ICE guided cardiac resynchronization therapy and the CHOICE trial
A Slee
17:30-17:50
Subcutaneous defibrillator: clinical evidence and current practice
R Cappato
17:50-18:10
Reverse remodeling of the left atrium with dual site right atrial pacing
R Nagarakanti
18:10-18:30
PANEL DISCUSSION

8:00-9:45
Session V: Catheter ablation and Treatment strategies in VT and Atrial Fibrillation:
clinical trials
(Co-Chairs): G Naccarelli & R Cappato
8:00-8:20
Concepts and Current Trial Status of VT ablation in Structural Heart Disease
B Singh
8:20-8:40
Dronedarone – Trial status and perspective
G Naccarelli
8:40-9:00
FREEZE and Fire&ICE: Is the Cryo-Ballon “hot”?
E Hoffmann
9:00-9:20
Is Mortality the key outcome for AF therapy trials?
S. Saksena
9:20-9:40
Cryptogenic Stroke – The CRYSTAL AF Study
J Brachmann
9:40-11:00
Session VI: Heart failure clinical trials
(Co-Chairs): E Hoffmann & KK Sethi
9:40-10:00
Remote Heart Failure Monitoring in Device Patients
S Sack
10:00-10:20
New Sensor Technology for HF in Clinical Trials
D Lakireddy
10:20-11:00
CASTLE-AF: Is there an AF-HF dialogue?
J Brachmann
10:45-11:00
PANEL DISCUSSION
11:00-11:15
COFFEE BREAK
11:15-13:00
Session VII: Outcomes and Clinical Trials (Co-Chairs): Thorsten Lewalter & S Saksena
11:15-11:45
Key Note Lecture: History of Oral Anticoagulation
B Lüderitz
11:45-12:05
Boutique Indications for ICD´s: Channelopathies and uncommon cardiomyopathis
Davendra Mehta
12:05-12:25
Sillent stroke in catheter ablation procedures: outcomes and clinical trials
T Deneke
12:25-12:55 Periprocedural anticoagulation with dabigatran, rivaroxaban and apixaban
S Lévy
12:55-13:00
Closing Remarks: Sanjeev Saksena